Applications
Mitochondria/Viruses/Plastids/Plasmids
Overview
The Genome Sequencer FLX System's ultra-high throughput and multiplexing capabilities afford a tremendous flexibility in experimental design for the sequencing of small genomes, viruses, plasmids, or mitochondria. These samples can be sequenced with unprecedented throughput and speed, sequencing tens to hundreds on a single GS FLX Instrument run. The system's long reads typically enable the assembly of shotgun sequence data into a minimal number of contigs.
Publications
- Hoffmann et al. DNA bar coding and pyrosequencing to identify rare HIV drug resistance mutations. Nucleic Acids Research 35: e19. 2007.
- Wang et al. Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance. Genome Research 17: 1195-201. August 2007.
- Gilbert et al. Whole-Genome Shotgun Sequencing of Mitochondria from Ancient Hair Shafts. Science 317:1927-30. September 28, 2007.
Click here to see all Mitochondria/Viruses/Plastids/Plasmids publications.
Data Analysis tools:
GS De Novo Assembler Software, GS Mapper Software