Neandertal Learning Materials:
- Neandertal Genome Fact Sheet
- A Quick Guide to Neandertal Biology
- How Genome Sequencing is Done
- From the Genome to the Proteome
- Glossary of Terms
Scholarly articles on Neandertal:
- Analysis of one million base pairs of Neanderthal DNA Richard E. Green, Johannes Krause, Susan E. Ptak, Adrian W. Briggs, Michael T. Ronan, Jan F. Simons, Lei Du, Michael Egholm, Jonathan M. Rothberg, Maja Paunovic and Svante Paabo
Nature, 2006 November 16; vol. (7117), 444 330-336 - Sequencing and Analysis of Neanderthal Genomic DNA James P. Noonan, Graham Coop, Sridhar Kudaravalli, Doug Smith,Johannes Krause, Joe Alessi, Feng Chen, Darren Platt, Svante Pääbo,Jonathan K. Pritchard, and Edward M. Rubin
Science, 2006 November 17 ; vol. 314, 1113-1118 - Neandertal DNA Sequences and the Origin of Modern Humans. Matthias Krings, Anne Stone, Ralf W. Schmitz, Heike Krainitzki, Mark Stoneking, and Svante Paabo. Cell, Vol. 90, 19–30, July 11, 1997
- No Evidence of Neandertal mtDNA Contribution to Early Modern Humans. David Serre, Andre Langaney, Mario Chech, Maria Teschler-Nicola, Maja Paunovic, Philippe Mennecier, Michael Hofreiter, Goran Possnert, Svante Paabo PLOS Biology. March 2004, Volume 2, Issue 3, Page 0314.
- Genetic Analysis from Ancient DNA. Svante Paabo,Hendrik Poinar, David Serre, Viviane Jaenicke-Despres, Juliane Hebler, Nadin Rohland,Melanie Kuch, Johannes Krause, Linda Vigilant, and Michael Hofreiter. Annu. Rev. Genet. 2004. 38:645–79
- Publications by Dr. Svante Paabo
Biographies:
The robust composite skeleton of a Neandertal (left) is unmistakably different from that of a modern human (right). G.J. Sawyer and Blaine Maley
Credit: Ken Mowbray and Blaine Maley, American Museum of Natural History.
Staff completing sequencing projects at the 454 Sequencing Center located in Branford, CT. Source: 454 Life Sciences.
Due to sample contamination, the task of sequencing the Neandertal genome is much more extensive than the task of sequencing the human genome. 454 Life Sciences' Genome Sequencer 20 System makes such an endeavor feasible by allowing approximately a quarter of a million single DNA strands from small amounts of bone to be sequenced in only about five hours by a single machine.
Source: 454 Life Sciences.
